The COVID-19 wasdeclared as pandemic on March 11 2020 by WHO., which proved to be the most pervasive and deadliest pandemic of 21st century. The flu-like illness resulted in millions of deaths. Coronavirus is a respiratory virus, which means that it infects a host through the pulmonary pathway. Droplet expulsions from an infected patient (cough, sneeze, spit) releases the virus into the air and the surrounding non-infected person can breathe in the virus particle, continuing the infection chain. Contact between individuals had to be minimized completely to stop the virus from spreading from one person to another. So, as an effective measure of “breaking-the-chain”, several of the countries issued partial and complete lockdown. Along with stringent local/international travel restrictions, frequent use of sanitizers, washing hands, wearing personal-protective-equipment (PPE), are being advised to the personnel working in this situation, especially the forces of law, medical staff, and persons associated with essential services. The pandemic has caused major disruption and devastation to the lives, expectations and livelihoods of people all over the world. This article attempts to explore the various effects of the COVID-19 lockdown on different sectors such as manufacturing, economy, education, social life, mental health, etc.