1Department of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Odisha, India
2Department of Biotechnology, School of Engineering and Technology, Centurion University of Technology and Management, Odisha, India
Article Publishing History
Received: 11/10/2020
Accepted After Revision: 28/12/2020
In this work, a Schiff base ligand namely 4-((2-(piprazine-1-yl)ethyl)pent-2-en-2-ol (HL) has been synthesized. Further the reaction between HL and NiCl2.6H2O salts has resulted in Schiff base complex with general formula [Ni(L)].Cl. The ligand HL and the corresponding Ni(II) complex was further characterized using various spectroscopic techniques, such as, FT-IR, ESI-MS, and elemental analysis. In the recent scenario, research in the field of protein dynamics is very crucial as these are the major part of the biological systems, and interactions of those macromolecules are responsible for various pathological diseases. Most of the metals inside the biological system shows some kind of affinity to bind with those macromolecules. Herein, it is our unmet need to address the issue by preparing some metal complexes. Therefore, fluorescence spectroscopy was introduced to check the protein binding study of BSA using Stern-Volmer equation.
Schiff Base, Bsa Using Stern-Volmer.