Bioscience Biotechnology Research Communications

An Open Access International Journal

P-ISSN: 0974-6455 E-ISSN: 2321-4007

Bioscience Biotechnology Research Communications

An Open Access International Journal

Bibin Kurian, Shalini Lokhande, Darshana Kumari Wankhede and Lalzampuii

Department of Child Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of
Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra, India.

Corresponding author email:

Article Publishing History

Received: 12/04/2021

Accepted After Revision: 05/06/2021


The most common intra-abdominal and extra-cranial solid tumour in children is neuroblastoma, derived from a neural crest. The etiology is not known, but there are family cases and neurofibromatosis, hirschprung disease, and friedreich ataxia are related, etc.  A 4 years old, female child was admitted on 7.1.2020 at BJWHC, Mumbai for the second dose of intravenous Immunoglobulin (IvIg). Incoordinate walking, abnormal eye movements, speaking difficulty. WBC: 14.95 10^3/UL, Lymphocytes: 4.77 10^3/UL, Hb: 10.6g/dL, Platelets: 332 10^3/UL, ALT/SGPT: 18 IU/L, Ultrasonography: Abdominal Mass, Biopsy: S/o Extra-Adrenal Neuroblastoma. Inj. Human Normal Immunoglobulin 5% 2mg/kg IV x OD. the condition of patient was improved after treatment was given. Her eye movements and way of walking were gradually improved. Patient was admitted to Paediatric Ward XV, BJWHC, Mumbai with a known case of Neuroblastoma. Follow-up treatment were started and condition of patient was improved.


Neuroblastoma, Neurofibromatosis, Hirschprung Disease, Friedreich Ataxia, Immunoglobulin.

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