Covid-19 are 65 nm to 125 nm in diameter and contain single-stranded RNA as nuclei content. Covid-19’s global scale transmission, frequent occurrence, large number of deaths The virus was primarily transmitted from person to person by physical interaction. Coughing, sneezing, and laughing cause droplets. Fever, chills, cough, sore throat, breathing difficulties, myalgia or fatigue, nausea, vomiting, and diarrhoea are common signs of COVID-19 infection. Study Of Liver Function Test, Haematological Parameters And Crp Derangements in Covid-19 patients 25 patients were ICU and 25 patients were ward. Patients went directly to the Observed Treatment in the Dept. of Medicine and Dept. of Respiratory, Datta Meghe Medical College and Shalinitai Meghe Hospital and Research Centre, However differences between the ICU and Ward liver function test, LDH ferritin and CRP patients were (P <0.0001) statistically significant Excepts total protein and albumin are not significant. (P= 0.4403, P= 0.3465) The literature considers the deranged values of liver function enzymes in Covid-19 to be of less concern, while our study shows a connection between liver enzymes and the increased number of ICU admissions as well as prognostic markers, necessitating further research in this area to document the derangements of liver enzymes during hospitalization and their relationship to clinical outcomes.