The most common intra-abdominal and extra-cranial solid tumour in children is neuroblastoma, derived from a neural crest. The etiology is not known, but there are family cases and neurofibromatosis, hirschprung disease, and friedreich ataxia are related, etc.  A 4 years old, female child was admitted on 7.1.2020 at BJWHC, Mumbai for the second dose of intravenous Immunoglobulin (IvIg). Incoordinate walking, abnormal eye movements, speaking difficulty. WBC: 14.95 10^3/UL, Lymphocytes: 4.77 10^3/UL, Hb: 10.6g/dL, Platelets: 332 10^3/UL, ALT/SGPT: 18 IU/L, Ultrasonography: Abdominal Mass, Biopsy: S/o Extra-Adrenal Neuroblastoma. Inj. Human Normal Immunoglobulin 5% 2mg/kg IV x OD. the condition of patient was improved after treatment was given. Her eye movements and way of walking were gradually improved. Patient was admitted to Paediatric Ward XV, BJWHC, Mumbai with a known case of Neuroblastoma. Follow-up treatment were started and condition of patient was improved.