Tuberculosis is a worldwide public health problem that affects people from all walks of life, including those in the United States, where it is more frequent among immunocompromised patients and other high-risk groups. Tuberculosis is a disease that can be active or latent. Postprimary tuberculosis occurs after a long period of latent infection. Lymphoma, pulmonary consolidation, and pleural effusion are the most prevalent symptoms of primary tuberculosis in children and immunocompromised adults. Nontuberculous mycobacterial disease might have symptoms that are similar to active tuberculosis, necessitating a test to establish the diagnosis. It is critical to be familiar with the imaging, clinical, and laboratory aspects of tuberculosis to diagnose and manage the disease. Mycobacterium Tuberculosis directly affected the lungs & many symptoms are seen as discuss earlier like Sweat, Loss of weight Cough, Fever, etc. Also the modern techniques are included, several drugs are given to TB patients. Multidrug- and extended-drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) is a major public health concern that jeopardises TB treatment and control progress.