Bioscience Biotechnology Research Communications

An Open Access International Journal

P-ISSN: 0974-6455 E-ISSN: 2321-4007

Bioscience Biotechnology Research Communications

An Open Access International Journal

Heenu Dhar and Poonam Salwan

Department of Pharmacology Shree Guru Gobind Singh Tricentary
University, Gurugram, Haryana, India

Corresponding author email: heenu_fmhs@sgtuniversity.org

Article Publishing History

Received: 19/05/2021

Accepted After Revision: 29/07/2021

ABSTRACT:

Viral diseases are becoming deadlier day by day, Dengue is one the major re-emerging disease which affects not only rural but it affects a large population in urban areas too. This disease not only pose a threat to the developing countries, but also affects a large amount of people worldwide. This disease has become a major priority for the world health organisation. Every year a large amount of humans die due to unavailability of proper vaccine against this disease. Natural products have always played an important role in treating various viral and bacterial disease. Phyto-compounds are an approach to cure this disease and can help further to develop a vaccine against it. One of them is found in Boesenbergia Rotunda commonly known as Chinese ginger. One of major constituents of Chinese ginger is 4-hydroxypanduratin A. 4-hydroxypanduratin A has been used as neuro-protective, strong antioxidant, antibacterial and antifungal. In this research, in-silico studies has been performed to check whether 4-hydroxypanduratin A is a compound of interest or not.

KEYWORDS:

4-hydroxypanduratin A, Autodock, Atomic contact energy,Boesenbergia Rotunda, Dengue Virus (DENV).

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