1Department of biochemistry, Datta Meghe Medical College, Nagpur.
2\Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe) Wardha.
3Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe) Wardha.
4Department of biochemistry, Datta Meghe Medical College, Nagpur, India
Corresponding author email: email@example.com
Article Publishing History
Accepted After Revision: 05/06/2021
According to the World Cancer Research Fund, reduce alcohol consumption, increasing physical activity, and maintaining a healthy weight will prevent 38 percent of breast cancer cases in the United States. Breast cancer screening is the process of monitoring otherwise healthy people for breast cancer in the hopes of catching it early. This research could help develop blood-based biochemical markers for breast cancer diagnosis and monitoring. To assess biochemical parameters in breast cancer patients. The findings were compared to those of stable controls. A clinical-based case control research was carried out between February 2020 and December 2020. A control group of 50 seemingly safe people was contrasted to a study group of 50 breast cancer patients from the Shalinitai Meghe Hospital in Nagpur. Kidney function tests, Liver function tests, Oxidative Stress Biomarkers, and Serum Antioxidant Levels in patients with breast cancer were studied using blood samples collected from the groups.
The results suggest that the increased mean values of serum alkaline phosphatase and serum glutamate oxaloacetate transaminase, as well as lower serum protein levels in breast cancer patients, are caused by the patients’ malignant stage. Increased TBARS (MDA) levels indicate increased lipid peroxidation/oxidative stress, which can lead to tissue damage and a breakdown of the antioxidant protection mechanism to prevent excessive free radical formation. The function of the renal profile in breast cancer patients will gain new dimensions as a result of these findings of elevated mean level. The majority of the patients diagnosed with breast cancer in the cases examined were from rural areas. The illness progressed due to a lack of knowledge of the diagnosed disorder in comparison to the surrounding areas. Breast cancer self-screening is a successful major if it is advertised to the interiors and peripheries to reduce the increased number of breast cancer patients.
Vitamin A, TBARS, MDA, SGOT, ROMs, SOD, GPx.