Bioscience Biotechnology Research Communications

An International  Peer Reviewed Refereed Open Access Journal

P-ISSN: 0974-6455 E-ISSN: 2321-4007

Bioscience Biotechnology Research Communications

An Open Access International Journal

Hirkani Shyam Chhadi1, Prajakta Warjukar2 and Nandkishor Bankar3 

1First Year MBBS Student Datta Meghe Medical College, Nagpur.

2Department of Biochemistry Datta Meghe Medical College, Nagpur.

3Department of Microbiology Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe) Wardha.

Corresponding author email: drprajaktaw@gmail.com

Article Publishing History

Received: 10/04/2021

Accepted After Revision: 08/06/2021

ABSTRACT:

The COVID-19 epidemic first discovered in December 2019 in Wuhan, China Also known as SARS COV-2 and also associated with mild to severe respiratory disease conditions India became the second most affected by Covid 19 with 12.6 million cases and 1.6 k death to date. Maharashtra offers the highest load status of Covid -19 in the india reporting category for all cases. It is a systemic disease involving various systems such as the heart, respiratory system, intestines, nerves, hematopoietic and immune systems. The disease exhibits variable clinical studies from mild to severe. Most patients have no symptoms, patients with comorbiditities have increased clinical decline and death and this is the group of patients we need to diagnose. Numerous studies have shown that many laboratory parameters that are easily accessible and inexpensive, can adequately predict the severity of the disease at an early age. In a country with limited resources such as India, costly investigations could not be carried out in this epidemic. It is necessary for patients to be assessed on these simple and inexpensive parameters specified in this review.

During the lymphocyte count process tests a complete blood count showed that lymphopenia was a basic laboratory detection that emerged as a negative predictor factor. Neutrophil lymphocyte levels also have predictive value in determining critical cases. Some of the inflammatory symptoms including LDH, CRP, IL-6 and serum ferritin also indicate cases of malignant speculation and require immediate intervention to improve survival. Serum ferritin levels were higher in patients with severe covid-19 than in patients with non-malignant illness. D-dimer levels were consistently elevated in reported instances and were found to be associated to the severity of the disease. The most common laboratory diagnoses found in covid patients 19 increased CRP, increased D-dimer, decreased albumin, increased ESR, decreased eosinophils, increased IL6, lymphopenia and LDH. These patients need urgent care and need to be transferred to intensive care units.

KEYWORDS:

SARS COV-2, Covid-19, CRP, D-Dimer.

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