Jan 03, 2020 0 comment

Influence on Diabetic Pregnant Women with a Family History of Type 2 Diabetes

Sameera A. Al-Ghamdi1,2

1Department of Biological Sciences, Faculty of Science,

2Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdulaziz University, Jeddah, Saudi Arabia.

Corresponding author email: saalghamdi17@gmail.com


Received: 07/10/2019

Accepted: 29/11/2019

ABSTRACT:Gestational diabetes mellitus (GDM) is defined as diabetes that only progresses during pregnancy and resolves after delivery. Family history (FH) of type 2 diabetes mellitus T2DM is one of the major risk factors for GDM. The aim of this study was to compare GDM between women with and without FH of T2DM. In this study, 137 GDM;150 non-GDM women were involved. Anthropometric and biochemical data were recorded. Calculation analysis confirmed the negative impact with the FH of T2DM between GDM (58.4%) and non-GDM (56%) women (p=0.97). Negative association was observed when the GDM cases with family history of T2DM was compared with GDM without family history of T2DM (p=1.01). However, age, FBG, and PPBG levels were p<0.05; BMI was non-significant (p=0.22). In conclusion, this study disclosed FH of T2DM did not affect GDM in women in an Indian population.

KEYWORDS:Gestational diabetes mellitus, Family history, Type 2 diabetes mellitus, Obesity, Indian population