Bioscience Biotechnology Research Communications

An International  Peer Reviewed Refereed Open Access Journal

P-ISSN: 0974-6455 E-ISSN: 2321-4007

Bioscience Biotechnology Research Communications

An Open Access International Journal

Bidyut Kumar1, Nitesh Dhar Badgayan2 and  PVPS Arun3

1Department of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Odisha, India

2School of Vocational Education and Training, Centurion University of Technology and Management, Odisha, India

3Department of Biotechnology, School of Engineering and Technology, Centurion University of Technology and Management, Odisha, India

DOI:

Article Publishing History

Received: 12/10/2020

Accepted After Revision: 23/12/2020

ABSTRACT:

In this work, a Schiff base ligand namely 4-((2-(piprazine-1-yl)ethyl)pent-2-en-2-ol (HL) has been synthesized. Further the reaction between HL and NiCl2.6H2O salts has resulted in Schiff base complex with general formula [Zn(L)].Cl. The ligand HL and the corresponding Zn(II) complex was further characterized using various spectroscopic techniques, such as, FT-IR, ESI-MS, and elemental analysis. In the recent scenario, research in the field of protein dynamics is very crucial as these are the major part of the biological systems, and interactions of those macromolecules are responsible for various pathological diseases. Most of the metals inside the biological system shows some kind of affinity to bind with those macromolecules. Herein, it is our unmet need to address the issue by preparing some metal complexes. Therefore, fluorescence spectroscopy was introduced to check the protein binding study of BSA using Stern-Volmer equation.

KEYWORDS:

Schiff Basebase, Biological Systems, Metals, Inside the Biological.

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